CORONAVIRUS including Severe Acute Respiratory Syndrome (SARS Virus), 2019 nCoV (Wuhan) and other new varients - VADS CORNER

 

 

Vads Corner- CORONAVIRUS - including SARS-CoV, 2019 nCoV (Wuhan) and newer varients

This page is dedicated to Severe Acute Respiratory Syndrome (SARS) and now to other new human cornaviruses. It was setup as a result of the recent outbreak in Canada, China, Hong Kong Special Administrative Region of China, Indonesia, Philippines, Singapore, Thailand, and Viet Nam.. This page will be updated when information is available. You are welcome to suggest links or comments related to this site by e-mailing directly to me or mentioning the link in the guestbook. I however have the right to moderate these links. Initial news indicated it may belong to a paramyxovirus group and the latest news now confirms it is a new Coronavirus. Please read the disclaimer.

Suggest for updates, see links in italics or Updates as I may not have the time to update! Please sign my guestbook below if you find this site useful.

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Last Updated 4th Feb 2020

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Latest News Updates on SARS, 2019-nCoV and other new human Coronaviruses

 

Criteria to Guide Evaluation of Patients Under Investigation (PUI) for 2019-nCoV

Patients in the United States who meet the following criteria should be evaluated as a PUI in association with the outbreak of 2019-nCoV in Wuhan City, China
Clinical features and epidemiologic risk
Clinical Features & Epidemiologic Risk
Fever1 and symptoms of lower respiratory illness (e.g., cough, difficulty breathing) and In the last 14 days before symptom onset, a history of travel from Wuhan City, China.

– or –

In the last 14 days before symptom onset, close contact2 with a person who is under investigation for 2019-nCoV while that person was ill.

Fever1 or symptoms of lower respiratory illness (e.g., cough, difficulty breathing) and In the last 14 days, close contact2 with an ill laboratory-confirmed 2019-nCoV patient.

The criteria are intended to serve as guidance for evaluation. Patients should be evaluated and discussed with public health departments on a case-by-case basis if their clinical presentation or exposure history is equivocal (e.g., uncertain travel or exposure).

Source: https://www.cdc.gov/coronavirus/2019-nCoV/clinical-criteria.html

Case Definition of Severe Acute Respiratory Syndrome (SARS)

Case definitions (revised 1 May 2003)

Suspect case
1.   A person presenting after 1 November 20021 with history of:
-  high fever (>38 °C)
AND
-   cough or breathing difficulty
AND one or more of the following exposures during the 10 days prior to onset of symptoms:
-  close contact2 with a person who is a suspect or probable case of SARS;
-  history of travel, to an area with recent local transmission of SARS
-  residing in an area with recent local transmission of SARS

2.  A person with an unexplained acute respiratory illness resulting in death after 1 November 2002,1 but on whom no autopsy has been performed
AND one or more of the following exposures during to 10 days prior to onset of symptoms:
-  close contact,2 with a person who is a suspect or probable case of SARS;
-   history of travel to an area with recent local transmission of SARS
-  residing in an area with recent local transmission of SARS


Probable case

1.  A suspect case with radiographic evidence of infiltrates consistent with pneumonia or respiratory distress syndrome (RDS) on chest X-ray (CXR).
2.   A suspect case of SARS that is positive for SARS coronavirus by one or more assays. See Use of laboratory methods for SARS diagnosis.
3.   A suspect case with autopsy findings consistent with the pathology of RDS without an identifiable cause.

Exclusion criteria
A case should be excluded if an alternative diagnosis can fully explain their illness.

Reclassification of cases
As SARS is currently a diagnosis of exclusion, the status of a reported case may change over time. A patient should always be managed as clinically appropriate, regardless of their case status.
-   A case initially classified as suspect or probable, for whom an alternative diagnosis can fully explain the illness, should be discarded after carefully considering the possibility of co-infection.
-   A suspect case who, after investigation, fulfils the probable case definition should be reclassified as "probable".
-   A suspect case with a normal CXR should be treated, as deemed appropriate, and monitored for 7 days. Those cases in whom recovery is inadequate should be re-evaluated by CXR.
-   Those suspect cases in whom recovery is adequate but whose illness cannot be fully explained by an alternative diagnosis should remain as "suspect".
-   A suspect case who dies, on whom no autopsy is conducted, should remain classified as "suspect". However, if this case is identified as being part of a chain transmission of SARS, the case should be reclassified as "probable".
-   If an autopsy is conducted and no pathological evidence of RDS is found, the case should be "discarded".

1   The surveillance period begins on 1 November 2002 to capture cases of atypical pneumonia in China now recognized as SARS. International transmission of SARS was first reported in March 2003 for cases with onset in February 2003.

2   Close contact: having cared for, lived with, or had direct contact with respiratory secretions or body fluids of a suspect or probable case of SARS.

Source: http://www.who.int/csr/sars/casedefinition/en/

Organisation with information

Information on 2019 -nCoV

Information on SARS

Clinical/ Epidemiology Information

Pathology and Laboratory SARS

Medical Publications - 2019 nCoV

Medical Publication - SARS

Other SARS Resources

Coronaviridae Source CDC.Coronavirus particles.

Paramyxovirus - For more information

Influenza - For more information and links related to influenza

H5N1 Avian Influenza - Bird Flu - For more information.

Country Coverage (Links may be broken and have not been updated - kept for historical reasons)

Hong Kong Coverage- SARS

CHINA Coverage- SARS

Singapore Coverage -SARS

Canada Coverage - SARS

Australia Coverage - SARS

French Coverage - SARS

UK Coverage - SARS

Eurosurveillance - SARS

Taiwan - SARS

Malaysia - SARS

New Zealand Coverage - SARS

Respiratory ProtectionThe chest roentgenogram typically shows diffuse bilateral infiltrates. Source: The Internet Journal of Emergency and Intensive Care Medicine TM

News Online : Read the following newspapers for updates. (Links may be broken and kept for historical reasons)

Worldwide Outbreak Resources

MEDLINE abstracts (NLM PubMed)

Source: National Center For National Biotechnology Information(NCBI). When you read the MEDLINE (NLM PubMed) abstract click on Links: Related Articles.

SARS

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Virology sites

Communicable Disease Control, Surveillance and Other Resources

Resource Articles

Medline Search Sites, Medical Journals Site and Search Engines

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First up on 18 March 2003.

Last Updated 4th Feb 2020

Home

Software

Hindu

Malaysian

Kids

Cybermed

Japanese Encephalitis

Dioxin

Paramyxoviridae

Manipal Alumni

Web Search

SARS

Medline

Med. Journal

Medical

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West Nile Fever

Arsenic

Chikungunya Virus

Haze

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